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A randomized, double-blind, placebo-controlled trial in 153 older adults taking the antidepressant citalopram found daily supplementation with 500 g vitamin B 12 , 2 mg of folic acid, and 25 mg of vitamin B6 for one year did not reduce the severity of depressive symptoms but increased the response to drug treatment and helped to prevent symptom relapse (112), suggesting B-vitamin supplementation might provide some benefit as an adjunct therapy
These side effects usually subside on their own within a few days
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Vitamin B12 is obtained through food sources such as beef, liver, chicken, fish (trout, salmon, tuna, clams), fortified breakfast cereals, lowfat dairy products, and eggs
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