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In practical terms, tirzepatide does three things: Slows how quickly food leaves your stomach, so you feel full longer Reduces appetite signals from the brain, so cravings drop Improves how your body uses insulin, which helps blood sugar control It's given as a weekly injection under the skin, starting at a low dose and stepping up over several weeks to a target of 5 mg, 10 mg, or 15 mg per week

The FDA-approved maintenance doses for weight management are 2.4 mg weekly (standard) or 1.7 mg weekly (alternative if higher dose not tolerated)

Common triggers include: Eating too quickly or consuming large meals Very hot, spicy, or cold foods Carbonated drinks Emotional stress or sudden excitement Smoking or swallowing excess air The characteristic sound happens when the vocal cords close abruptly to stop additional air from entering the lungs

Wegovy, a drug approved by the U.S

Circulation (2013) 127(1):7485