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In animal models, pulsatile GH administration preferentially activates growth-promoting pathways, while continuous GH favors fat metabolism and can lead to receptor desensitization
B12 injections deliver hydroxocobalamin (the preferred formulation in the UK) or cyanocobalamin directly into muscle tissue, bypassing the gastrointestinal tract to ensure rapid absorption into the bloodstream
For separate detection of the two forms, a portion of the sample was treated with 5% 2-vinylpyridine (Sigma) for 60 min to trap GSH
10.1016/j.freeradbiomed.2012.03.011 58 FryeR
As a cytoprotective agent, mediating Roberts cytoprotection, it maintains endothelium integrity and has a particular angiomodulatory effect (Sikiric et al., 1993
