The Link Between GLP-1 Drugs and NAION Recent studies have suggested a potential increased risk of pharmaceutical related NAION associated with GLP-1 medication use
For the new study, published in Science Translational Medicine , Martin Berg, a cell biologist at the University of Gothenburgs Sahlgrenska Cancer Center in Sweden, and his colleagues decided to look at melanoma because rates have been increasing and because the cancer is known to be sensitive to the effects of free radicals
Colonic L cells contain twice as much GLP-1 peptide than proximal intestine L cells (Reimann et al., 2008)
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Investigations assess encapsulation methods, individual absorption kinetics, peptidepeptide interactions, enteric-coating systems, excipient compatibility, and other delivery technologies designed to preserve peptide integrity and improve experimental bioavailability