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Beyond weight outcomes, the Phase 2 obesity trial also reported improvements in several cardiometabolic markers, including: Reductions in waist circumference Improvements in fasting glucose and insulin sensitivity Favourable changes in blood pressure and lipid profiles Phase 3 trials understood to form part of the TRIUMPH programme are now underway, evaluating retatrutide in broader populations including people with type 2 diabetes and cardiovascular disease
Lenti MV, Rugge M, Lahner E et al (2020) Autoimmune gastritis
Even moderate-intensity strength work paired with adequate protein significantly reduces lean mass loss compared to sedentary weight loss approaches
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Because semaglutide is administered via subcutaneous, understanding proper injection techniques is critical
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