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Future outlook Research into GLP-1 patches is progressing quickly, with several pharmaceutical companies reporting positive results from preclinical and early human studies

Semaglutide cut major cardiovascular events by 20% in people with obesity and existing heart disease but no diabetes, and the benefit showed up early, before most of the weight came off

Combination chemotherapy produces chemical oophorectomy in the majority of premenopausal women over the age of 40 52 resulting in lower circulating estradiol levels compared with premenopausal patients taking tamoxifen alone