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These patterns act as ligands for pattern recognition receptors (PRRs) expressed on the microglial surface, most notably Toll-like receptors 2 and 4 (TLR2 and TLR4) and triggering receptor expressed on myeloid cells 2 (TREM2) [54]

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Another study on intranasal administration of BPC-157 in rats with rhinitis elicited anti-inflammatory effects in the nasal lining [17, 18]

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