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Put simply, the more body fat we accumulate, the deeper we trap ourselves in a vicious cycle
In addition to their peripheral actions, GLP-1Rs are also expressed throughout the central nervous system, particularly within hypothalamic nuclei, septal regions, the brainstem and at lower levels in various cortical structures (Pyke et al., 2014
To facilitate inter-mice statistics, each rs-fMRI image was spatially smoothed (0.5 mm isotropic Gaussian kernel), and each voxels time series was bandpass filtered from 0.01 to 0.3 Hz [40, 41]
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What specific mechanisms underlie its effects
After this point, you risk a gradual decline in potency, which can introduce yet another unwanted variable into your experiments
