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IL-13 exerts its anti-angiogenic function via activation of protein kinase C (PKC) / II and ERK-1/2, with concomitant down-regulation of the NF-B/p65 pathway (90), and it also can reduce the death of chondrocytes to protect the cartilage from destruction probably because of the reduction of Fc gamma receptor I (FcRI) (91)

Approach marketing claims accordingly and expect gradual, modest changes over months rather than rapid transformation

While limited in scope, this preliminary data suggests the preclinical findings may translate to human applications

If they cannot or will not share COAs, look elsewhere