What I saw in the data was that most of these side effects peaked during dose escalation and then settled down
Dehydration can worsen nausea and create a problematic cycle
It turned out to be possible to go beyond the traditional use of GLP-1 and GLP-1RAs for the treatment of T2DM, metabolic syndrome, and obesity, since these compounds affect the liver, pancreas, brain, fat cells, heart, and gastrointestinal tract [107]
Br J Pharmacol 177(3):656667
Most people are more comfortable taking a pill than regularly injecting themselves, says Daniel Drucker, an endocrinologist at the University of Toronto, who previously consulted for Novo Nordisk