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I'm just going back to the interesting work because the malate being the short chain fatty acid and Mark Shigenaga showing, this is all in animal research, by the way

S2CID 206140413

The purpose of the epithelium is to allow the digestion and absorption of dietary nutrients while keeping unwanted toxins, microbes and food particles from passing directly into the body

Additionally, the sympathetic nervous system may have a complex mechanism that inhibits the effects of oxidative stress represented by ferroptosis

For IBS, leaky gut, or inflammatory bowel conditions, the oral or sublingual troche is the first-choice route