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As a result, these materials address the shortcomings of other hydrogel-based depot technologies as they exhibit: (i) mild formulation requirements favorable for maintaining drug stability during manufacturing and storage, (ii) pronounced shear thinning properties enabling injection through clinically-relevant needles, (iii) rapid self-healing of hydrogel structure and depot formation mitigating burst release of the drug cargo, (iv) sufficiently high yield stress to form a robust depot that persists under the normal stresses of the subcutaneous space following administration, and (v) prolonged delivery of therapeutic cargo ( 45 )
Post-procedure recovery in aesthetic medicine, after laser treatments, microneedling, or surgical procedures, is one of the most practical applications
Following implantation of the pump, three-chamber testing was performed on day seven of infusion, OFA test was performed on day nine, marble burying was performed on day fourteen and weight was also measured on day fourteen of the infusion
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