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To overcome these challenges, strategies 5 such as pH optimization, use of stabilizing excipients (buffers, antioxidants, surfactants), lyophilisation, and controlled storage conditions are employed
One key thing to remember is that everyones body responds differently to medications
Patients received arGLP-1 based on availability and clinical appropriateness: semaglutide was administered via weekly subcutaneous injections, starting at 0.25 mg/week and titrated to a maximum dose of 1 mg/week, while dulaglutide was administered at a fixed dose of 1.5 mg/week
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1 x Composite major CV events were analyzed in a time-to-first-event analysis with a Cox proportional-hazards model with treatment as a categorical fixed factor and stratified according to SGLT-2i use as baseline
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