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GHK-Cu is a photolabile copper(II) complex, and freeze-thaw cycling can disrupt the copper coordination sphere independently of any damage to the peptide backbone

Tuy nhin, tnh an ton v lu di vn cha c kim nghim v cn thm nhiu th nghim lm sng na

Cannon B, Nedergaard J

It is entirely possible that the slight rise in optic nerve issues reflects the underlying, advanced vascular damage or high baseline cardiovascular strains already present in patients who require these stronger medications, rather than a direct toxic effect of the drug molecules themselves

This represents an opportunity to reduce opioid prescribing and facilitate tapering in appropriate patients