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L-Serine 1.3 g
71.2 lbs on average) Retatrutide 9mg: 26.4% body weight reduction Tirzepatide/Zepbound (Phase 3 comparison, not head-to-head): ~20.9% Semaglutide/Wegovy (Phase 3 comparison, not head-to-head): ~14.9% Placebo: ~2.1% Note: These figures come from separate Phase 3 trials and are not direct head-to-head comparisons
Results depend on adherence, provider guidance, lifestyle changes, metabolic health, underlying conditions, and consistency with the care plan
But they price and structure that access very differently
References Reviewed Brass EP, Hiatt WR
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