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The more serious side effects are complex gastrointestinal (GI) issues, vision loss, and DVT
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Although a significant proportion of the weight is regained after cessation, the results of our modelling suggest that some benefit is maintained for at least 1 year, however there is likely significant variation at the individual level
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On the other hand, there have been some case reports of drug-induced lupus associated with GLP1-RA use, in particular with semaglutide, so further study is warranted15
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