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Based on the current observational associations, further experimental validation in clinical and in vitro models is needed to directly assess causal links across tissues and to explore the precise connection between these two pathways

Reduction in Inflammation in Lipedema Anti-inflammatory Effects: GLP-1 agonists can help lower inflammation, a common lipedema issue, by improving metabolic health and reducing adipose tissue

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No difference in adverse events was observed with the SGLT2i combination in the respective Harmony Outcomes and AMPLITUDE-O post-hoc analyses

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