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2.5 mL vial at 5 mg/mL (12.5 mg total semaglutide): 5 mL vial at 5 mg/mL (25 mg total semaglutide): At maintenance doses (1.7 to 2.4 mg), you go through vials faster

- People with significant liver disease (the 9-month monkey toxicology study showed dose-dependent periportal vacuolation in hepatocytes that the FDA flagged as a possible safety signal)

While it offers similar benefits, its not FDA-approved, so quality and effectiveness can vary depending on which pharmacy is compounding it

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