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J Clin Endocrinol Metab 2002;87:3578-82.
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Metformin is commonly used as first-line therapy unless contraindicated or poorly tolerated, but the addition of glucose-lowering therapies with different mechanisms of action is usually needed to provide adequate glycemic control [1,2,3], with the choice of agent being dependent on multiple factors, such as cost and the presence of comorbidities [1]
Liraglutide exposure is also modestly increased in hepatic impairment, though the FDA did not mandate specific dose adjustments [1]
Puri, P
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