Dosing & Reconstitution Guide Educational guide for reconstitution and weekly dosing Standard / Gradual Approach (3 mL = ~10.0 mg/mL) Frequency: Inject once weekly subcutaneously [1] [2]
They address different problems and, in some cases, work best together when used thoughtfully and appropriately
Given the lack of predictable efficacy in the context of serious AEs, the risks/ burdens of this type of hydrodistension outweigh benefits
95% CI: 1.10, 1.35), while risks of mortality and overall major adverse cardiac events (acute myocardial infarction, cerebral infarction, and/or mortality) were reduced (respectively, HR 0.48 with 95% CI of 0.28, 0.80
After establishing baseline response for 4-6 weeks, discuss nausea management strategies with your provider before making changes