14 BrownEHeerspinkHJLCuthbertsonDJWildingJPH
CD31: cell adhesion molecule
Stimulation of GLP-1R with exendin-4 in the PBN reduces food intake and therefore decreases body weight in rats
The efficacy and safety of weekly semaglutide (2.4 mg) for the treatment of overweight and obesity was investigated in the Semaglutide Treatment Effect in People with Obesity (STEP) programme, which included individuals with overweight (BMI 27 kg/m 2 ) and complications, including dyslipidaemia, hypertension, sleep apnoea, cardiovascular disease and type 2 diabetes, or individuals with obesity (BMI 30 kg/m 2 ) with or without complications [26, 34,35,36,37,38,39]
While it might be tempting to try just to see, dont go rogue