Cartilage degeneration was scored using the Yoshimi scale, which ranges from 0, defined as normal cartilage, to 5, defined as complete loss of cartilage
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Enhanced expression of IL-8 in normal human keratinocytes and human keratinocyte cell line HaCaT in vitro after stimulation with contact sensitizers., tolerogens and irritants
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Importantly, BPC-157 also induces expression of EGR-1 and its corepressor NAB2, forming a regulatory feedback loop that modulates the duration and amplitude of angiogenic gene transcription during wound healing