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Pale skin Heart palpitations Shortness of breath A smooth tongue Vision loss Constipation Loss of appetite Diarrhea Gas Vision loss Mental problems like depression, memory loss, or behavioral changes Nerve problems like numbness or tingling, muscle weakness, and problems walking

SURMOUNT-1 demonstrated average body weight reductions of 15% at the 5mg dose, 19.5% at 10mg, and 20.9% at 15mg over 72 weeks, compared to 3.1% with placebo

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Pharmacy and geographic location : The prices of brand-name drugs may vary depending on the pharmacy and region

In addition, the authors thank Lindsay Uglow of Spirit Medical Communications Group Limited for medical writing and editorial assistance (funded by Novo Nordisk A/S) and Christin Lth Hertz of Novo Nordisk for reviewing the manuscript