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The medication requires careful dose titration based on thyroid function tests (TSH, free T4), and patients with primary hypothyroidism often need lifelong treatment, though some conditions (such as postpartum thyroiditis) may be transient

For clinical and manufacturing leaders, that means developing a coordinated manufacturing network strategy that is reliable across regional disruptions, not relying on single suppliers, and balancing the manufacturing load across locations

Professional organizations, including the American Podiatric Medical Association, are expected to issue clinical guidance for practitioners managing GLP-1 users