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First, optimal patient selection criteria remain poorly defined

These multidisciplinary clinics typically combine medication management with nutritional counseling, behavioral therapy, and exercise guidancean integrated approach that optimizes outcomes

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[32] : 316321, 344348 Techniques [edit] To reduce pain associated with the procedure, medical staff may apply a topical local anaesthetic (such as EMLA or Ametop) to the skin of the chosen venipuncture area about 45 minutes beforehand