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When hydroxocobalamin is given in high doses (such as during cyanide poisoning treatment), unique effects can be observed: patients often experience a transient reddening of the skin or mucous membranes and a reddish discoloration of the urine due to drug excretion

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This recommendation is particularly apt when the compound in question lacks any pediatric approval or trial data

the field has since advanced to triple agonists like retatrutide