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Industry activity suggests rapid development in this area [14], but clinical adoption will depend on functional benefits, safety, cost-effectiveness and regulatory guidance
Our study also found that NRF2, GPX4 and SOD1 expression levels were higher in the neoadjuvant chemotherapy-resistant group compared to the sensitive group, further supporting our hypothesis and demonstrating the adverse effects of GSH on chemotherapy in breast cancer patients
Many of our patients were undergoing MAD throughout the course COVID-19 pandemic, which affected routine follow-up appointments and lab measurements
Other GLP-1R agonists have demonstrated extensive pleiotropic effects, including benefits in managing comorbidities such as osteoarthritis, cardiovascular disease, and neurodegenerative disorders
Trimethylamine-N-Oxide induces vascular inflammation by activating the NLRP3 inflammasome through the SIRT3-SOD2-mtROS signaling pathway
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