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[1] After 21 days at room temperature, the pen must be discarded even if the original expiration date has not been reached
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The article describes the reaction peaking about 15 to 30 minutes after injection and fading as the medication disperses and local inflammation resolves
This desensitization is one reason some patients experience a plateau effect where appetite suppression weakens despite increasing doses
Cohen S, Cummings J, Knox S, Potashman M, Harrison J
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