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Mol Psychiatry 22 , 328335 (2017)

Phadnis, V

Sleep optimization strategies include maintaining consistent sleep-wake schedules, creating optimal sleep environments (cool, dark, quiet), limiting blue light exposure in evening hours, avoiding caffeine in the afternoon and evening, managing stress through relaxation practices, and addressing any underlying sleep disorders such as sleep apnea with appropriate medical treatment

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The critical limitation for both compounds is the same: evidence is preclinical, human clinical data is either minimal (BPC-157) or nonexistent (KPV), and both are sourced through unregulated markets where product quality cannot be guaranteed