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315,316,317 GLP-1R is expressed in human monocyte-derived macrophages and the mouse macrophage cell line RAW264.7
The compound is based on the active fragment of endogenous GLP-1 with structural modifications that improve stability
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Kahn MA, Weathers DR, Hoffman JG
Se han reportado complicaciones de retinopata diabtica con semaglutida, probablemente relacionadas con la reduccin rpida de la glucemia en pacientes con retinopata preexistente, similar a lo observado con insulina
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