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Short-Term Side Effects of GHB Common immediate effects reported with GHB, GBL, or 1,4-BD use include: Sedation, drowsiness, and reduced responsiveness Confusion, impaired judgment, and memory problems, including amnesia Dizziness, nausea, and vomiting Slowed breathing and decreased heart rate Loss of coordination and fainting Mood changes ranging from euphoria to agitation Long-Term Effects of GHB With repeated or frequent use, people often develop tolerance and physical dependence