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Reduced food noise: The mental quieting of food preoccupation allows patients to make more deliberate food choices rather than responding to constant hunger signals

This risk is primarily driven by the rapid weight loss these medications produce, which changes bile composition and reduces gallbladder motility

Hormones and therapeutics that act in part via the hypothalamus have made tremendous waves in the past year, underscoring the importance of endocrine regulation in the pathophysiology and treatment of prevalent metabolic disorders such as obesity, diabetes, and fatty liver disease, Abel concludes

NICE guideline NG28 for type 2 diabetes and technology appraisals for weight management formulations emphasise the importance of patient education and individualised care when initiating GLP-1 therapy

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