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Seek medical advice if you experience: Severe or persistent nausea and vomiting that prevents adequate food or fluid intake Signs of dehydration , including dark urine, dizziness, or reduced urination (this can potentially lead to acute kidney injury if severe) Unexplained abdominal pain , particularly severe pain in the upper abdomen that may radiate to the back (potential pancreatitis) Visual changes or symptoms of diabetic retinopathy worsening Symptoms of hypoglycaemia (low blood sugar), especially if taking Ozempic alongside other diabetes medications Right upper abdominal pain, fever or yellowing of the skin/eyes , which could indicate gallbladder problems (cholelithiasis or cholecystitis) [1] [4] Allergic reactions , including rash, itching, or swelling Regarding weight loss and appearance concerns , contact your GP if: Weight loss is excessively rapid (more than 1 kg per week consistently) You are experiencing significant nutritional deficiencies or difficulty maintaining adequate nutrition Facial or body changes are causing significant psychological distress You wish to discuss adjusting your treatment plan to slow the rate of weight loss Importantly, do not abruptly reduce or stop insulin if you are also using insulin therapy, as this could lead to diabetic ketoacidosis

G-protein signaling (inside the cell)

B., Lentino, C

This is a potentially dangerous condition called hypoglycemia unawareness

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