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However, when sold for "research" or "anti-aging" purposes outside of its approved indication, it falls into a regulatory gray area
Laforge, M
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[Ends] 31/10/2024 Notes for editors Research: Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors for recurrent nephrolithiasis among patients with pre-existing nephrolithiasis or gout: emulation of two target trials doi: 10.1136/bmj-2024-080035 Journal: The BMJ Funding: National Institutes of Health, Canadian Institutes of Health Research Link to Academy of Medical Sciences press release labelling system: Externally peer reviewed
A 2025 meta-analysis looking at 13 randomized trials concluded that yerba mate supplementation reduced postprandial (after-meal) glucose levels and improved insulin resistance markers in people with pre-diabetes
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