This means there are both weight-dependent and weight-independent effects on the heart. The level of benefit in the study is close to what was observed in another trial, SELECT, which looked at reductions in heart events in people taking semaglutide for weight loss
Sikiric P, Rucman R, Turkovic B, Sever M, Klicek R, Radic B, et al
The FDA is not legally bound to follow the committee's recommendation and has previously diverged from PCAC consensus, though doing so is uncommon
The point isn't that any of these ingredients are dangerous in normal amounts
On the other hand, those who travel frequently might prefer a pill over carrying injection supplies