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Unlike orlistat (which can worsen diarrhoea in post-cholecystectomy patients) or very low-calorie diets (which can be difficult to digest), Wegovy works primarily through lowering hunger rather than fat malabsorption
Encouraging patients to use sweeteners in moderation helps prevent potential negative consequences
The major proglucagon fragment: an abundant islet protein and secretory product
Once inside, they: Reduce neuroinflammation (inhibit NFB, microglial activation) Boost synaptic plasticity (enhance neuron connectivity) Improve glucose uptake (support brain energy metabolism) Local GLP-1 from neurons likely doesnt drive these effectspharmacological action dominates
As such, its possible for a product to be unsafe, ineffective, or both
