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Activation of the GLP-1 receptors in the nucleus of the solitary tract reduces food reward behavior and targets the mesolimbic system

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On the cellular level, proliferation (quantified by number of Ki67-positive cells per crypt) remained unchanged as well as the number of mucin-producing goblet cells (identified by PAS/AB staining) ( Figure 5C )

it may reduce the effectiveness of oral contraceptives during initiation/dose escalation