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Both agents remain underresearched in human populations
In hypothyroidism, about 15 20% of patients report fatigue or brain fog even after correction of thyroxine levels to normal with levothyroxine (2528)
For fat loss and metabolic effects, consistent use over several weeks may be needed
What's most concerning in the Journal of Clinical Investigation study was that L-carnitine supplementation, even among vegan/vegetarians, has an effect on gut microbiota and can increase TMAO
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