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Regulatory control or oxidative damage

The FDA prescribing information for tirzepatide includes a specific warning about acute kidney injury due to dehydration associated with gastrointestinal adverse reactions

Due to its dual-agonist mechanism, it may be preferred for patients who need to lose a more significant amount of weight or have not achieved desired results with other treatments

However, the medication's gastrointestinal side effects and reduced food intake may indirectly affect iron status