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N and C terminal Modifications Exenatide Exendin-4 is a 39-amino acid peptide sourced from the venom of the Heloderma lizard, boasting a 53% homology with native human GLP-1 (Fig

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GLP-1(1-37) is confirmed to be a highly potent agonist of the GLP-1 receptor (GLP-1R) by measuring the expression of the luciferase reporter gene expression in transiently transfected human embryonic kidney (HEK293) cells [1]