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LPS-Salycilate=56
The non-binding recommendation differs from FDA staff briefing materials, which had proposed that the substances should not be included
, , ,
4c, replacement of the first six residues of GLP-2 by those of GLP-1 (i.e., double mutant D 3P E and S 5P T) decreased cAMP accumulation by 12-fold compared to the native peptide, suggesting that subtle substitution may directly alter receptor activation
The coefficient of variation was determined by dividing the standard deviation (SD) of the glucose levels by the mean glucose level (MGL) and multiplying by 100 [29]
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