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What Reviews and Reddit Say The clinical data is clear, if modest
The company states that interim results from the ongoing phase 1b study assessing multiple ascending doses of GUBamy are expected during the first half of 2025 [117]
However, using oral arginase inhibitors long-term to promote NO production may be challenged by the lack of isoform specificity, making it difficult to balance the roles of arginase isoforms in the urea cycle and NO production and potential disruption of nitrogen metabolism (Pudlo et al., 2017)
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