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The landscape is evolving quickly

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In April 2024, the European Medicines Agency's Pharmacovigilance Risk Assessment Committee (PRAC) concluded that available evidence does not support a causal association between GLP-1 receptor agonists (including Wegovy) and suicidal thoughts or behaviours, following a comprehensive review of clinical trial data and post-marketing surveillance reports

Further research is needed to resolve uncertainties regarding the specific metabolic alterations and to achieve a comprehensive understanding of how GLP-1RAs affect metabolism and the underlying molecular pathways