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People who are unable to absorb vitamin B-12 properly may have pernicious anemia, which is a type of anemia characterized by a lack of intrinsic factor

A minus 2.5% work RVU efficiency adjustment also applies to established codes like 96372, which slightly reduces the work RVU component used in the payment calculation

However, each additional compound adds variables

Among them, the synthetic tetrapeptide AEDG (Ala-Glu-Asp-Gly, Epitalon) has been obtained from a natural peptide called epithalamin, produced in the pineal gland [13]

However, the absence of human clinical trials means the relevance and safety of these mechanisms in humans remains unestablished