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Randomised clinical trials on vitamin B 12 in pregnancy are called for as concluded in a recent systematic review and meta-analysis.22 This trial will add to the knowledge on the potential beneficial effects of vitamin B 12 on pregnancy and perinatal outcomes.21 Our results can be used to inform both regional dietary guidelines for Nepalese and South Asian pregnant women
In the SURPASS trials (focused on type 2 diabetes), 15 mg of tirzepatide reduced HbA1c by up to 2.58 percentage points, bringing many participants to normal glycemic levels
The rectal administration is also beneficial for patients who may have difficulty swallowing pills or for those who have gastrointestinal issues that could interfere with the absorption of oral medications
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