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GLP-1 stimulates insulin secretion, inhibits glucagon secretion, slows gastric emptying, and promotes satiety, all of which contribute to weight loss

Quick Answer: GLP-1 affects multiple brain regions including the hypothalamus, brainstem, mesolimbic reward system, hippocampus, and cortical areas involved in appetite regulation, reward processing, and cognitive function

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Diabetologia 55 (10), 25932603