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Because thiamine sits at the centre of carbohydrate metabolism and normal nerve conduction, a shortfall can appear as reduced appetite, muscle weakness, poor coordination, a faster heart rate and other neurological signs

PubMed laboratory research record [PMID: 4724072] PubMed record related to this compound for laboratory literature review

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Two significant long-term complications can arise from severe or chronic pancreatic damage: Exocrine Pancreatic Insufficiency (EPI): The pancreas loses its ability to produce digestive enzymes, leading to poor nutrient absorption, weight loss, and diarrhea

J Phys Chem B (2009) 113:355664