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The drug primarily targets serotonergic and dopaminergic activity, and its co-effectiveness in alleviating depression and aggression further suggests potential shared mechanisms underlying these symptoms
It is noteworthy that long-term HFD consumption may differentially regulate NF-B activity in hepatocytes (inhibition) and Kupffer cells (activation by lipopolysaccharide)
-Synuclein has been identified as a major protein component of Lewy bodies and plays a significant role in the pathogenesis of PD [219]
Nanomed (Lond)
So when the body gets overloaded and the liver starts storing fat, that's a problem
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