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A major challenge in the development of bispecific antibodies, such as CD3 T-cell engagers (TCEs), is optimizing biological potency with pharmacology and manufacturability
The gap between these two peptides isn't subtle
Ruilope L
Bettge, K., Kahle, M., Abd El Aziz, M
Native GLP-1 functions as a rapid-response, meal-related hormone with a half-life measured in minutes, while semaglutide is an engineered therapeutic agent with a half-life measured in days
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