Thioredoxin reductases (TXNRDs) employ NADPH as an electron donor to revert oxidized TXN to a reduced dithiol, the oxidation status of which is critically implicated in regulating various cell behaviors including proliferation and apoptosis 51
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Bexarotent attenuated chronic constriction injury-induced spinal neuroinflammation and neuropathic pain by targeting mitogen-activated protein kinase phosphatase-1
GABA has three receptors, i.e., GABAA, GABAB, and GABAC, on the post-synaptic neurons (Briggs and Galanopoulou, 2011), and among them, GABAA is of critical importance as this receptor is involved in controlling and balancing action potential and main target of the AEDs
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